Chidzidzo chitsva kubva kuRNA
Munguva pfupi yapfuura, tsvakurudzo yakawana kuti genetic variantsizvo zvinoderedza mazinga ekugadzirisa eRNA akasungwa kaviri anobatanidzwa ne autoimmune uye immune-mediated mamiriro.
RNA mamorekuru anogona kugadziriswa. Semuenzaniso, nucleotides inogona kuiswa, kubviswa, kana kuchinjwa. Imwe yeanonyanya kugadziriswa, iyo tsvakurudzo itsva inoratidza inoita basa rinokosha mukutanga kwechirwere chechirwere, ndiko kuchinjwa kwe nucleotide adenosine mu inosine mukati meRNA yakapetwa kaviri. Chidzidzoaivarakabudiswaon Nyamavhuvhu 3 muZvisikwa inoburitsa kuti genetic variants iyo inoderedza iyi chaiyo shanduko inosanganiswa nenjodzi yakawedzera ye autoimmune uye immune-mediated kuzvimba kusagadzikana senge psoriasis, kuzvimba bowel chirwere, uye Type 1 chirwere cheshuga. Vanyori vanokurudzira kuti puroteni ye sensor inogona kukanganisa aya mashoma-akagadziridzwa maRNA emamorekuru ekunze, zvichikonzera mhinduro yekuzvimba.
Molecular biologist yaifunga izvozvo'zvirokwazvo budiriro huru, uye yakawanikwaiyo "inoshamisa kwazvo" kukosha kweRNA kugadzirisa kunoratidzika kunge kune zvirwere zvinoputika, zvichienzaniswa nekutaura kwemajini kana kuputika.
Ichokwadi tsvakurudzo huru. Uye sekutengesa zvigadzirwa zve electrophoresis, ndiri kuda kuziva kuti chii chinonzi RNA, uye kuti masayendisiti anoongorora sei RNA ne electrophoresis? Iyo inonyatso hunyanzvi uye ruzivo rwandisingazive kwandiri asi zvakadaro zvinonakidza kuiongorora.
Chii chinonzi RNA?
RNA, ipfupi yeRibonucleic acid, nucleic acid iripo mumasero mapenyu ese. Kusiyana neDNA, RNA inowanzova imwe chete. Basa rayo guru nderekuita senhume inotakura rairo kubva kuDNA yekudzora kuumbwa kwemapuroteni, kunyangwe mune mamwe mavhairasi RNA kwete DNA inotakura ruzivo rwemajini.
Agarose Gel Electrophoresis yeRNA
Vanhu vanogonakuongorora kunaka kweRNA negel electrophoresis.
Beijing Liuyi Biotechnology Co.Ltd, ainyanzvi inogadzira inotarisa pane zvigadzirwa zve electrophoresis makore anopfuura makumi mashanu, inopa huwandu hwematangi e electrophoresis (makamuri / masero) egel electrophoresis, senge horizontal electrophoresis matangi (makamuri / maseru) eagarose gel electrophoresis, uye vertical electrophoresis matangi (makamuri / masero) protein gel electrophoresis. Zvichakadaro, inopawo mhando dzakasiyana dze electrophoresis magetsi emagetsi, kabati rima bhokisi analyzer uye UV transilluminator. Unogona kusarudza Beijing Liuyi's electrophoresis matangi (makamuri/masero) kuyera huremu hwemamorekuru eRNA uye kupatsanura RNA yehukuru hwakasiyana hwerabhoritari yako.
Pano isu tichasuma imwe yemhando yakachinjika electrophoresis tank (chamber/sero) modhi DYCP-31DN kubva kune edu makumi matatu nerimwe zvigadzirwa.
DYCP-31DN idiki saizi horizontal electrophoresis tank(chamber/sero) yekuyera huremu hweRNA kana DNA nekuiparadzanisa.
| Dimension (LxWxH) | 310×150×120mm |
| Gel Size (LxW) | 60 × 60mm 60 × 120mm 120 × 60mm 120 × 120mm |
| Comb | 2+3 matsime (2.0mm) 6+13 matsime, 8+18 matsime 11+25 matsime |
| Comb Ukobvu | 1.0mm, 1.5mm uye 2.0mm |
| Nhamba YemaSamples | 2-100 |
| Buffer Volume | 650 ml |
| Kurema | 1.0kg |
Iine matireyi mana egel akasiyana ekugadzira 4 saizi dzakasiyana dzemagero. Iyo yakasarudzika dhizaini yemacombs inosangana nezvinodiwa zvakasiyana zvemasample matsime. Iyo buffer volume inosvika 650ml. Ishoma huwandu hwemhinduro yebuffer, asi yakanyanya nyore kushanda uye ine mari kushandisa. Ndiyo imwe yezvigadzirwa zvedu zvinopisa zvekutengesa. Inokodzera sarudzo yako.
Beijing Liuyi Biotechnology Co.Ltd zvakare inogona kupa OEM gel matangi. If iwe unoda tsika-yakagadzirwa electrophoresis tank / sero / kamuri, Liuyi Biotechnology inogona kukupa yakanakisa OEM sevhisi.
Iyo Liuyi mhando ine makore anopfuura makumi mashanu nhoroondo muChina uye kambani inogona kupa yakagadzikana uye yemhando yepamusoro zvigadzirwa pasi rese. Kupfuura makore ebudiriro, yakakodzera sarudzo yako!
Kuti uwane rumwe ruzivo nezvedu, ndapota taura nesu neemail[email yakachengetedzwa] or [email yakachengetedzwa].
Mareferensi eAgaroseGel Electrophoresis yeRNA
1. Kushaikwa kweRNAKugadzirisa Inobatanidzwa muChirwere Chinopisa by Alejandra Manjarrez
Nguva yekutumira: Aug-15-2022